Login Form

Cabaser, Dostinex (Cabergoline)

Trade Names: Cabaser, Dostinex
Chemical Names: Cabergoline
Routes: Oral

Cabergoline was developed in the 1980s and is a selective dopamine receptor agonist with a strong affinity for the dopamine D2 receptor. Dopamine normally serves as a negative feedback for prolactin release, so cabergoline effectively inhibits prolactin secretion by mimicking the actions of dopamine on the D2 receptor.

As a targeted agonist of the dopamine D2 receptor, cabergoline should not affect other pituitary hormones like growth hormone (GH), luteinizing hormone (LH), corticotrophin (ACTH), or thyroid stimulating hormone (TSH).

Bodybuilders using Trenbolone or Nandrolone often experience increased levers of prolactin and that may lead to a number of side-effect like impotence, infertility and sometimes gynocomastia. Since prolactin is a lactation hormone it may cause lactating gynocomastia. This disorder is often characterized by small fluid discharge that becomes noticeable with the squeezing of one's gynocomastia nipple.

Cabergoline is very effective in reducing or eliminating side-effects associated with high prolactin levels. An initial dosage of 500mcg (0.5mg) is usually given per week. After 4 weeks the dosage may be increased to 1mg per week. Normally 4 to 6 weeks is sufficient and the drug may be discontinued.

The most common side-effects associated with cabergoline are headache, nausea and vomiting. Less common side-effects way include constipation, dry mouth, abdominal pain, diarrhea, dizziness, fatigue, anxiety, anorexia, depression, insomnia, hot flashes, heart palpitations, hypotension, breast pain, and acne.

In South Africa, cabergoline is only commercially available as Dostinex (2x 0.5mg tablets) and is very expensive. The generic known as Cabaser is sometimes imported and sold on the blackmarket for a fraction of Dostinex's price. Cabaser is sold in 1, 2 and 4mg variations; however the 1mg tablets are the most common.