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Parlodel (Bromocriptine)

Trade Names: Parlodel
Chemical Names: Bromocriptine mesylate
Routes: Oral

Bromocriptine mesylate (Parlodel) is an ergot derivative with D2 dopamine receptor agonist and D1 dopamine receptor antagonist activities. It was first used in the 1970s as a prolactin inhibitor for treatment of Parkinson’s and also a growth hormone (hGH) suppressant when high dosages are used.

Bodybuilders use it for its ability to inhibit prolactin. This is useful when using steroids like Trenbolone and Nandrolone. Those two hormones may elevate prolactin levels causing a number of side-effects like impotence, infertility and sometimes lactating gynocomastia. Personally, I feel that Cabergoline is much better suited for this purpose, because it has less side-effects and a better dosing regimen.

Author, Lyle McDonald described in his book how Parlodel can be used to normalize the slowing metabolism during calorie restricted dieting. The body use Leptin levels as a measurement of the current amount of adipose tissue stored as well as the amount of calories consumed. When dieting, leptin levels lower significantly and thus the body will respond by holding on to nutrient stores, this is often why dieting plateaus are experienced. Maintaining normal leptin stimulation could be key to keeping any diet productive and bromocriptine may indeed allow us to do that.

For fat-loss or prolactin inhibition a dosage of 2.5 to 5mg is normally used daily. Side-effects are common and many users prefer to start on 1.25mg per day and only increase the dosage when the initial nausea side-effects go away. Other very common side-effects include low blood pressure, dizziness and confusion. Less common adverse reactions include anxiety, dry mouth, edema, seizures, fatigue, headache, lethargy, nasal congestion, rash, elevated liver enzymes, and changes in urinary frequency.

Bromocriptine is not widely diverted for sale on the black market, but can be found circulating on occasion.