Lipotropic injections

  • N3rd
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04 Jan 2010 11:02 #32256 by N3rd
Lipotropic injections was created by N3rd
Hi all,
may you have a happy new year full of blessed workouts :)
There are people that I know who have achieved excellent results with "lipotropic" or "anti-obesity" injections.
As far as I have researched the ingredients are:
L-Methionine
Inositol
Choline
as well as B12
BUT
it may also be hCG (Pregnyl) ?!?!?!


These injections are given subcutaneously with an insulin syringe, 10 - 12 per session, causing spot reduction of fat, which is then urinated out of your body (pink urine).

Any info please:
Is this a scam (placebo effect)?
Brand names / product names?
Legality of this stuff?
Can you get it at a pharmacy if it is legal, according to google? (No asking for sources ;) )
If it works so well, and has basically no side-effects, why don't BB'ers use it?

The only success I had product wise was this name M.I.C. Injections....
per 2ml:
L-Methionine 50mg
Inositol 100mg
Choline Chloride 100mg
Benzyl 1.5%
50ml vial

Thank you B)

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  • SNOK1986
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04 Jan 2010 11:46 #32257 by SNOK1986
Replied by SNOK1986 on topic Lipotropic injections
Yeah i know of people using HCG for fat loss but what u mentioning sounds strange, where did u get that ifno from? post up the link if possible :)

No lets not deadlift as I need a double hip replacement haha

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04 Jan 2010 14:09 #32267 by N3rd
Replied by N3rd on topic Lipotropic injections
SNOK1986 wrote:

Yeah i know of people using HCG for fat loss but what u mentioning sounds strange, where did u get that ifno from? post up the link if possible :)


Which info?
People getting lipotropic injections
www.lipotropicsinjections.info and word of mouth
or the MIC product?
(some list of recalled products that I can't seem to find again)

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  • Yohimbe
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04 Jan 2010 17:55 #32286 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
I read about the HCG diet, but it sounds ridiculous. They have them on 500 calories a day. Doesn't matter what you take you're going to lose weight on 500 calories a day. And then have a huge rebound effect when you come off the diet.

I haven't heard of the lipotropic injections with HCG though. Can't see how HCG fits in with it-its supposed to be a concoction that dissolves subq fat.

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04 Jan 2010 18:01 #32289 by N3rd
Replied by N3rd on topic Lipotropic injections
Yeah, I don't think these people are using hCG.
I really want to know more about MIC injections.
MIC is also the main ingredient of Weider Fat Burner GT :
Inositol - 800mg
L-Methionine - 800mg
Choline Bitartrate - 600mg
This may only make your liver more effective at processing fats.
But MIC injections dissolve fat which is then (supposedly) urinated out...
:bounce

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  • Yohimbe
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04 Jan 2010 22:49 #32375 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
ezinearticles.com/?Lipotropic-Injections...--My-Story&id=828063

Some seem to think it works. I don't have any first hand experience though, but will look into it-am always looking for the Holy Grail of fat loss.

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04 Jan 2010 22:52 #32378 by N3rd
Replied by N3rd on topic Lipotropic injections
Yohimbe wrote:

ezinearticles.com/?Lipotropic-Injections...--My-Story&id=828063

Some seem to think it works. I don't have any first hand experience though, but will look into it-am always looking for the Holy Grail of fat loss.


Yes indeed, that article states what I already know.
Please continue the research :)
But people are not very willing to give out the exact product name... :(

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  • Inja
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05 Jan 2010 17:26 #32508 by Inja
Replied by Inja on topic Lipotropic injections
Hey bro,

There’s the Lipo-B injection and the Lipodissolve injecton.

The former fits the description of the ingredients listed above, vitamin b12 and b6, inositol, choline, methionine, etc… These are all compounds found naturally in all our bodily cells and they work in signalling pathways that promote energy production. This includes the breakdown of glycogen and fat stores. Like you said they are primarily used in oral supplements to increase the bodies fat metabolising function. Certainly by spot injecting you may build up higher concentrations in those cells and cause the fat cells to breakdown fat slightly faster in that locale, but I can’t see this as being very effective for spot reduction. Using a fat burner that targets the adrenergic pathways does the same thing, only I would think it to be better at it. Certainly there is not much medical proof in the way of using these compounds for spot injections.

The latter is far more successful, it a mix of Amphipathic compounds phosphatidylcholine and deoxycholine. This is the same stuff Doctors are using today to aid in the liposuction process by injecting before the operation. These molecules will bind to the fat stores and make them more soluble by coating the hydrophobic chains with hydrophilic head groups. These fats will then associate with bodily fluids and may or may not pass out through the urine. This is unfortunately the reason the FDA has not approved them and there is such scandal around these injections. Many are worried the solubilised fats may accumulate in the liver, or become bound to artery wall and build up plaques. This of course has serious impacts for overall health (liver function) and cardiovascular integrity (possible fatal heart attacks later in life). The latter is obviously more of a concern in sedentary individuals. Certainly this injection is much more effective at spot reduction, but there may or may not be a price to pay for this.

Sorry if I offend you
Its just my point of view

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  • Yohimbe
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05 Jan 2010 17:29 #32510 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
Inja wrote:

Hey bro,

There’s the Lipo-B injection and the Lipodissolve injecton.

The former fits the description of the ingredients listed above, vitamin b12 and b6, inositol, choline, methionine, etc… These are all compounds found naturally in all our bodily cells and they work in signalling pathways that promote energy production. This includes the breakdown of glycogen and fat stores. Like you said they are primarily used in oral supplements to increase the bodies fat metabolising function. Certainly by spot injecting you may build up higher concentrations in those cells and cause the fat cells to breakdown fat slightly faster in that locale, but I can’t see this as being very effective for spot reduction. Using a fat burner that targets the adrenergic pathways does the same thing, only I would think it to be better at it. Certainly there is not much medical proof in the way of using these compounds for spot injections.

The latter is far more successful, it a mix of Amphipathic compounds phosphatidylcholine and deoxycholine. This is the same stuff Doctors are using today to aid in the liposuction process by injecting before the operation. These molecules will bind to the fat stores and make them more soluble by coating the hydrophobic chains with hydrophilic head groups. These fats will then associate with bodily fluids and may or may not pass out through the urine. This is unfortunately the reason the FDA has not approved them and there is such scandal around these injections. Many are worried the solubilised fats may accumulate in the liver, or become bound to artery wall and build up plaques. This of course has serious impacts for overall health (liver function) and cardiovascular integrity (possible fatal heart attacks later in life). The latter is obviously more of a concern in sedentary individuals. Certainly this injection is much more effective at spot reduction, but there may or may not be a price to pay for this.


Do you think the fats are accumulated in the liver etc?

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  • Inja
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05 Jan 2010 21:52 #32545 by Inja
Replied by Inja on topic Lipotropic injections
The fats will pass into the blood or into the lymph and then blood. In the blood they will inevitably pass through the liver. It is inevitable the liver will pick some of these up. Likewise with so many fats passing through the blood chances for plaque formation are increased. The amount of fat that ends up in the wrong place is probably reliant on how much fat you dissolve, your cardiovascular health, liver function, etc...

Certainly athletes using AAS probably already have a fatty liver and poor lipid profile so the risk in these individuals is amplified.

Sorry if I offend you
Its just my point of view

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  • N3rd
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05 Jan 2010 22:25 #32552 by N3rd
Replied by N3rd on topic Lipotropic injections
Thanks, Inja.
Karma to you, hardworking dog...
Do you have a name for me?
Amphipathic compounds phosphatidylcholine and deoxycholine...

Or else I'll google it ;)

Anyway, what if you combine these Amphipathic injections with, MIC tablets and/or milk thistle to help the liver stay healthy and get rid of the dissolved/soluble fats...?

Lets try to reinvent fat burning...
Or not... ;) :P

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05 Jan 2010 22:51 #32557 by N3rd
Replied by N3rd on topic Lipotropic injections
Google tells me that phosphatidylcholine helps break down the fat and deoxycholine or deoxycholate makes the fat soluble.

Both occur naturally in the body, thus they shouldn't be toxic/dangerous (In reasonable amounts).

They should be legal to buy, but do you need a presciption?

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  • Yohimbe
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05 Jan 2010 22:56 #32559 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
This has tickled my interest-I found a site selling the kits, if I'm allowed to post-please remove if not.

www.mesotherapyworldwide.com/Injectables_Mesotherapy.htm#WW

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05 Jan 2010 23:05 #32560 by N3rd
Replied by N3rd on topic Lipotropic injections
Seems a little expensive...
But you are getting a lot of stuff for your money.
As soon as I can get hold of my local rep ;) , I'll ask him if these lipodissolve injections are the same as the ones he has.
Hang in there Yohimbe, we'll get to the bottom of this, I'm sure.
Lets hear what Admin knows (on 11 January :( ).

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05 Jan 2010 23:10 #32561 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
N3rd wrote:

Seems a little expensive...
But you are getting a lot of stuff for your money.
As soon as I can get hold of my local rep ;) , I'll ask him if these lipodissolve injections are the same as the ones he has.
Hang in there Yohimbe, we'll get to the bottom of this, I'm sure.
Lets hear what Admin knows.


Thanks man

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  • Inja
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06 Jan 2010 14:58 #32656 by Inja
Replied by Inja on topic Lipotropic injections
N3rd wrote:

Thanks, Inja.
Karma to you, hardworking dog...
Do you have a name for me?
Amphipathic compounds phosphatidylcholine and deoxycholine...

Or else I'll google it ;)

Anyway, what if you combine these Amphipathic injections with, MIC tablets and/or milk thistle to help the liver stay healthy and get rid of the dissolved/soluble fats...?

Lets try to reinvent fat burning...
Or not... ;) :P


A notion no more silly than an athlete ingesting a large quantity of liver toxic orals and then taking a little milk thistle and/or SAMe to try curb the carnage. The damage is still done, but it may be lessened. ;)

Any comments on my next post? Anything to add? Criticism, question, etc..?

Sorry if I offend you
Its just my point of view

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06 Jan 2010 15:04 #32657 by N3rd
Replied by N3rd on topic Lipotropic injections
What, on this post?
Nope.
Makes sense.
1 Q, who bashed your karma that I just gave you yesterday?
Did you and juiced have a go at each other again? :laugh:

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  • Inja
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06 Jan 2010 15:07 #32659 by Inja
Replied by Inja on topic Lipotropic injections
PCDC injections (lipodissolve, lipostabil)
by Inja :laugh:

The lipodissolve injection is made up of two primary components, phosphatidylcholine (PC) and deoxycholate (DC). To understand how these injections work we must remind ourselves of a basic scientific principle - like dissolves like. What this means is that fatty (hydrophobic) molecules will associate with fatty molecules and dissolve in fatty solvents (oil) while polar (hydrophilic) molecule will associate with polar molecules and dissolve in polar solvents (water). Some compounds such as detergents and surfactants are amphipathic in that they have both a hydrophilic end and a hydrophobic end. This allows them to dissolve fats in water by associating with both polar and non-polar compounds and is the principle behind why soaps are able to remove dirt.

Phosphatidylcholine along with other phospholipids are a natural component of cellular membranes. They associate with each other in a lipid bilayer so that their polar portion faces outward towards the solvent (water) while their fatty components make up the membrane interior. Body fat is stored in fat cells as triglycerides which have the same basic organisation as the lipids that make up cellular membranes. This means that phosphatidylcholine can associate with the stored fats in the body. Deoxycholate is a metabolite of the bile salts produced in the liver. Deoxycholate can also be used to emulsify fats by binding their long hydrophobic chains and essentially coating them with a polar face. This is actually the biological function of bile salts, facilitating the break down of dietary fats in the intestines.

(File Removed)
Figure: Ball and stick models of phosphatidylcholine (left), deoxycholate (centre), and triacylglycerol (right). The polar regions of the molecules are highlighted with light blue circles while the remaining molecules are made up of long hydrophobic alkyl chains.

In combination the PCDC mix will associate with stored fat molecules and essentially coat them in polar charges that make them water soluble. Body fat thus dissolves into the surrounding fluid and is taken up by the blood whether through surrounding capillaries or via the lymphatic system. Eventually these fats are eliminated from the body along with ones normal bowel movements. The primary controversy surrounding these injections is that their safety has not been yet proven and they are thus not endorsed by the FDA. There is a substantial risk that with all those fats circulating through the bloodstream at once one increases the likelihood of fatty deposition in the arterial walls and atherosclerosis. Of course this is quite ironic since the treatment was originally intended for intravenous administration with the aim of reducing pre-existing plaques. In addition the liver will pick up these fats and store them. An excessively high fat content in the liver (fatty liver disease) leads to an unhealthy liver, high blood pressure, and possibly liver cancer. Bodybuilders and alcoholics are already at risk of having a slightly fatty liver because of the drugs they take, for example steroids are known to negatively affect the users’ lipid profile and long term SERM use has also been attributed to the formation of a fatty liver. In order to implement some kind of damage control when using PCDC injections it is important to maintain a healthy diet that is very low in fat to prevent additional lipid accumulation in blood. In addition exercise and high fluid intake may help to prevent atherosclerosis. One might also consider the use of lipotropic combination formulae (usually containing methionine, inositol, choline, and B-vitamins) as well as other liver supporting compounds to increase the livers ability to metabolise and eliminate fatty complexes (Credit to N3rd).

In order for the actives in the PCDC to dissolve body fat they have to get into fat cells. They do this invasively by actually dissolving the cell membranes and killing the cells. Remember stored fats and cell membranes are made up of compound similar in structure. Thus PCDC injections are capable of dissolving not only fatty tissue but in fact any tissue it is injected into. As a result PCDC injections may also be used to help treat gynecomastia by dissolving the excess fat as well as the actual surrounding breast tissue. However PCDC injections can also digest muscle and skin tissue. Although the damage may be minimal often the damaged tissues are replaced with scarring, which to the bodybuilder may produce localised unsightly blemishes in muscle quality. Obviously an overall reduction in body fat is better achieved with good diet and training, with PCDC injections developing a niche in localised spot reduction of troublesome areas. That being said the risk of scarring and peripheral tissue damage is greatly increased given the limited volume and proximity to muscle tissue of these tiny fat pockets.

Sorry if I offend you
Its just my point of view

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06 Jan 2010 15:10 #32661 by Empire
Replied by Empire on topic Lipotropic injections
so inja do u think this stuff works in your opinion?

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06 Jan 2010 15:16 #32666 by N3rd
Replied by N3rd on topic Lipotropic injections

One might also consider the use of lipotropic combination formulae (usually containing methionine, inositol, choline, and B-vitamins) as well as other liver supporting compounds to increase the livers ability to metabolise and eliminate fatty complexes (Credit to N3rd).

:woot :)

I agree, that with these injections a low fat diet would be essential, because of all the fat circulating around.

:bow

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06 Jan 2010 17:19 #32685 by Inja
Replied by Inja on topic Lipotropic injections
djeasye wrote:

so inja do u think this stuff works in your opinion?


Lipotropic injections, no. Those will work as well as an oral supplement of the same nature for overall reduction. The lipodissolve product on the other hand must work for local spot fat reduction. Why else would the surgeons use it right?

If you search on other boards it seems some guys have great results with it while others not so much. Not sure why there is that variation though. In addition I can't find anything on the extent of tissue damage it might pose. This is not noticable with regular folk, but with a lean BB'er things might be very different on overall appearance...

Sorry if I offend you
Its just my point of view

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10 Jan 2010 00:32 #32995 by durbanguy
Replied by durbanguy on topic Lipotropic injections
were can i get the lipotropic injections done in south africa?Durban?

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10 Jan 2010 10:25 #33001 by Empire
Replied by Empire on topic Lipotropic injections
durbanguy wrote:

were can i get the lipotropic injections done in south africa?Durban?


you should find what u looking for here bro www.anabolicsteroids.co.za/forum/rules

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  • Inja
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10 Jan 2010 15:46 #33028 by Inja
Replied by Inja on topic Lipotropic injections
Of course we can't help you with underground sources but you can contact a cosmetic surgeon in your area to find out if he is willing to do them. I'm not sure how many surgeons in S.A. use injections for lipo instead of the traditional mechanical invasion, but there probably are some.

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Its just my point of view

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  • Yohimbe
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10 Jan 2010 16:00 #33032 by Yohimbe
Replied by Yohimbe on topic Lipotropic injections
djeasye wrote:

durbanguy wrote:

were can i get the lipotropic injections done in south africa?Durban?


you should find what u looking for here bro www.anabolicsteroids.co.za/forum/rules


:laugh: :laugh:

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