Official peptide thread

Muscleaddict wrote: So you're doing hexarelin with GHRP6? I chose ipamorelin because it doesn't have any effect on cortisol or prolactin. Hexarelin is the strongest GHRP so you get the biggest GH pulse, but you also get more prolactin and cortisol than the other GHRPs. Ideally you want to combine one GHRP (GHRP2/GHRP6/ipamorelin/hexarelin) with a GHRH like CJC1295 w/o DAC. There is no synergistic benefit in stacking different GHRPs like there is with a GHRP+GHRH. Rather add in an extra shot during the day than mix the hex/ghrp6.

I'm planning on doing:

Wake up: 100mcg ipamorelin + 100mg CJC1295 w/o DAC
Post workout: 100mcg ipamorelin + 100mg CJC1295 w/o DAC
Bed time: 100mcg ipamorelin + 100mg CJC1295 w/o DAC

On off days I'll probably do my shot before I go for a run to aid with fat burning. I'm still not 100% decided on how I'm gonna run it. Open to suggestions.

bud, thats pretty much exactly how i want to run a cycle in jan, im itching cause my shoulder is nagging me for it. but anyway, im highly interested to know what your take on it is when you start,

as for my method, will run the same as yours, BUT unsure about the second pin, as to either hit it pre or post WO, i have found highly conflicting views on both, :S

just remember carbs and fats blunt gh release, protein doesn't. don't pin too close to eating. 15-25 min after post workout pin consume your high protein shake.

ghrh/cjc will make the environment more suitable for gh release this means when combing a ghrp with cjc your wait time decreases to min 1 hour post meal. helpful if you pinning 100 times a day like gorilla.

PoisonedPulse wrote: as for my method, will run the same as yours, BUT unsure about the second pin, as to either hit it pre or post WO, i have found highly conflicting views on both, :S

I am going with post workout because this is when you'd get the most anabolic effect from the GHRP/GHRH. Reason being that weightlifting upregulates (increases the number of) the IGF-1 receptors in the worked out muscles temporarily, so immediately post workout is when muscle will react best to the increase in IGF-1 caused by the peptides. This is when you want the release of IGF-1 to peak so that you can get new muscle cells. You also want the IGF-1 as high as possible when you have your shake because it forces all the aminos/glucose into your muscles for growth.

Muscleaddict wrote:

PoisonedPulse wrote: as for my method, will run the same as yours, BUT unsure about the second pin, as to either hit it pre or post WO, i have found highly conflicting views on both, :S

I am going with post workout because this is when you'd get the most anabolic effect from the GHRP/GHRH. Reason being that weightlifting upregulates (increases the number of) the IGF-1 receptors in the worked out muscles temporarily, so immediately post workout is when muscle will react best to the increase in IGF-1 caused by the peptides. This is when you want the release of IGF-1 to peak so that you can get new muscle cells. You also want the IGF-1 as high as possible when you have your shake because it forces all the aminos/glucose into your muscles for growth.

Would the insulin spike not negate the effects of the GHRP? Also would the excessive IGF-1 levels not cause the release of somatostatin?

Muscleaddict wrote:

PoisonedPulse wrote: as for my method, will run the same as yours, BUT unsure about the second pin, as to either hit it pre or post WO, i have found highly conflicting views on both, :S

I am going with post workout because this is when you'd get the most anabolic effect from the GHRP/GHRH. Reason being that weightlifting upregulates (increases the number of) the IGF-1 receptors in the worked out muscles temporarily, so immediately post workout is when muscle will react best to the increase in IGF-1 caused by the peptides. This is when you want the release of IGF-1 to peak so that you can get new muscle cells. You also want the IGF-1 as high as possible when you have your shake because it forces all the aminos/glucose into your muscles for growth.

Koe007 wrote:

Muscleaddict wrote:

PoisonedPulse wrote: as for my method, will run the same as yours, BUT unsure about the second pin, as to either hit it pre or post WO, i have found highly conflicting views on both, :S

I am going with post workout because this is when you'd get the most anabolic effect from the GHRP/GHRH. Reason being that weightlifting upregulates (increases the number of) the IGF-1 receptors in the worked out muscles temporarily, so immediately post workout is when muscle will react best to the increase in IGF-1 caused by the peptides. This is when you want the release of IGF-1 to peak so that you can get new muscle cells. You also want the IGF-1 as high as possible when you have your shake because it forces all the aminos/glucose into your muscles for growth.

Would the insulin spike not negate the effects of the GHRP? Also would the excessive IGF-1 levels not cause the release of somatostatin?

You wait 15-30 minutes after the injection before you consume carbs so that the insulin spike does not minimize the GH release caused by the GHRP/GHRH.

Totally right that IGF1 stimulates somatostatin. Somatostatin won't have any effect on the GH that just been released by the GHRP/GHRH. It will just prevent any more GH release. The surge of GH from the GHRP/GHRH happens within minutes after injection and tapers off over a few hours.

What is special about GHRPs like ipamorelin vs GHRH is that they actually suppress somatostatin. So you can get a GH release from ipamorelin even when somatostatin would be preventing GHRH from working.

thanks for clearing that up bud, as with the shake you stated below, aswell as mornings, wake up and pin, 30 min later eat first meal? and the post workout pin, 30min later have a shake? pre bed will be fine as obviously dont eat till the next day, i do have a shake and fats etc before i sleep, but ill just move it awhile before i close my eyes, sound acceptable MA?

aswell, what cycle did you settle on to run with the peptides bud?

@poisonpulse: Im no MA, but I do my shot 30mins before bedtime, then at bedtime I eat - Someone on this forum told me thats enough time to pulse the gh...

I also do a shot when I wake for a piss...

and how do you find the frequent pinning? i worked out 6 months @ 3 pins a day, is well over 500 pins, gotta get creative with my injection sites

Bro those lil needles are fokol! I do triceps,quads and abs...

You get the 0,5ml syringes which have a 31G little needle thats nothing. then my pharmacy only had the 1ml's with 27G needles and thats not a lekke pin though, where there is less body fat like triceps you sometimes have to push that needle hard!

iv noticed different sizes too, its not the needle im worried as its tiny, just the inconvenience of finding 558 sites and to become a pin cushion haha

ok... so after some consideration, and the lingering curiosity about these peptides, (ipam + cjc) im going to run them now as a bridge between cycles, and hopefully get some recovery out of my shoulder before i look at another cycle and damaging it more, main goals will be to accurately log my experience of the peptides alone, recover my nagging shoulder aswell as maintain my previous cycle gains

my reasoning is that if i add it on cycle next year for the first time, i wont really be able to report on true gains as AAS will be a big factor in growth and fatloss, where as now i can monitor any gains or progress made, i think it makes alot more sense, IF i find any benefit from these two peptides over the next 12 weeks i will consider the continuation into my cycle in jan, now i just have a few questions if muscleaddict or abc or anyone with experience for that matter can help me with;

1. the timing of my pins (ill be running 100mcg ipam +cjc 3x daily) optimally morning, post workout and pre-bed... BUT my problem is this

i train in the evenings at 6pm, generally finish around 7.30-8 dependent on how full the gym is, so post workout shot would be around that time frame, would this not be too close to my pre-bed pin, as i generally sleep anywhere between 11-12ish, would pre workout be a better option (will be at around 5.50pm Ed) ??? so my 3 shots can be more evenly spaced through out day?

2. the food topic- to my knowledge calories should be avoided atleast 1.5-2 hours pre pin, and around 30 min post pin, is that a safe guidline to use? diet will be high in calories too so concerned about timing for carbs and fats.

thats the main two concerns for now, ill be getting enough to run for 6 weeks, and ill reassess from there.

i will update on any findings etc. looking to start from monday, im open to any and all suggestions so dont be shy;)

thanx

PoisonedPulse wrote: ok... so after some consideration, and the lingering curiosity about these peptides, (ipam + cjc) im going to run them now as a bridge between cycles, and hopefully get some recovery out of my shoulder before i look at another cycle and damaging it more, main goals will be to accurately log my experience of the peptides alone, recover my nagging shoulder aswell as maintain my previous cycle gains

my reasoning is that if i add it on cycle next year for the first time, i wont really be able to report on true gains as AAS will be a big factor in growth and fatloss, where as now i can monitor any gains or progress made, i think it makes alot more sense, IF i find any benefit from these two peptides over the next 12 weeks i will consider the continuation into my cycle in jan, now i just have a few questions if muscleaddict or abc or anyone with experience for that matter can help me with;

1. the timing of my pins (ill be running 100mcg ipam +cjc 3x daily) optimally morning, post workout and pre-bed... BUT my problem is this

i train in the evenings at 6pm, generally finish around 7.30-8 dependent on how full the gym is, so post workout shot would be around that time frame, would this not be too close to my pre-bed pin, as i generally sleep anywhere between 11-12ish, would pre workout be a better option (will be at around 5.50pm Ed) ??? so my 3 shots can be more evenly spaced through out day?

2. the food topic- to my knowledge calories should be avoided atleast 1.5-2 hours pre pin, and around 30 min post pin, is that a safe guidline to use? diet will be high in calories too so concerned about timing for carbs and fats.

thats the main two concerns for now, ill be getting enough to run for 6 weeks, and ill reassess from there.

i will update on any findings etc. looking to start from monday, im open to any and all suggestions so dont be shy;)

thanx

Like I said I haven't got experience with ipam/cjc, first injections tonight , But from what I've read you'll be fine doing pre workout injections instead of postworkout, but some guys say it makes then a bit sluggish during their workout and that their body gets used to it. It probably doesn't make that much difference if you do it pre/post. I'll be trying both to compare anyway.

The reasoning behind post workout shots is the same as why you'd inject IGF1 post workout. To take advantage of the upregulation of IGF1 receptors for growth, and the increased GH->IGF1 helps with transporting nutrients and aminos to your muscles. IGF1 receptors are only upregulated for a short amount of time after a heavy workout, so post workout shots should be done as soon as possible after your lifting session to take advantage of that if you do go for postworkout.

Regarding food, wait an hour after eating carbs before you inject and 2 hours after eating fats. 30 mins after injection you can eat, maybe 20. In studies on pigs maximum plasma concentration of GH after ipamorelin is 12 mins after injection and then it tapers off. Yea, not exactly a reliable comparison but just to give you an idea.

Thanks very much bud, I understand the logic and importance behind it, the unsure part is, could I pin post work out, and then again before bed, would it not be too close together? For example my pin ptotocol would look like this if I pinned post workout, morning (around 8.00am_ then post workout (7.30-8.00pmish) and then pre bed (11.30pm) ?