LesDoctor wrote: "A steroid with this alteration is commonly described
as a C-17 alpha alkylated oral, although the terms of methylated or ethylated
oral steroid are also used. The alkyl group cannot be removed metabolically[i.e though the liver],
and therefore inhibits reduction of the steroid to its inactive 17-ketosteroid
form by occupying one of the necessary carbon bonds. Before long,
pharmaceutical companies had utilized this advance (and others) to
manufacture an array of effective oral steroids including methyltestosterone,
Dianabol, Winstrol®, Anadrol 50®, Halotestin®, Nilevar, Orabolin, and
Anavar. The principle drawback to these compounds is that they place a
notable amount of stress on the liver, which in some instances can lead to
actual damage to this organ."
This would suggest that even if you were to inject it intravenously (essentially what sublingual administration is try to accomplish), it would still pass through the liver in it's C-17 alpha alkylated state and thus still cause strain. But I could be wrong.
I have seen the recommendation floating around. The idea would be for the sublingual administration to not undergo first-pass metabolism in the liver.
Should this be the case (that it won't bypass first hepatic pass), would injectable winstrol be as harsh as oral?
EDIT: lol just saw your addition. Yeah it would likely be rapidly absorbed. I would be happy to be the lab rat but unfortunately I do not have much reference to go off.
