which is safer?

I heard from many that an oral roid such as anavar are much more damaging to liver that injectables such as depotrone.
Not too sure whats the diff?

Jip, it is. The pil runs trhew your digestive system threw all your organs, thus causing a lot of stress on your internal organs. Your injectable goes directly into your blood stream, faster & more effective, because it doesn't need to travel as far as your injectable. If you are taking orals, make sure that you dring a lot of water.

look dont get the wrong impression from this but ALL steroids have their draw backs. Yes anavar might be liver toxic etc but thats one of the sides,depotrone isnt that toxic but it plays havoc with your testicular system,your skin,your hair,agression levels etc,so to put it out there ,all steroids have their pro's and cons...its all up to you to which one or combination that you use...

Thanks Kobus as they say they all got some sort of side effects.
How important is the use of anti estrogens while on a course of say depotrone or anaplex.
should i use something like Kessar during my cycle and maybe Clomid or HCG post cycle?

You can use that on PCT. It just helps you to get your balls back to normal, & help the little man up a bit better, & also helps your body to get your natural abilty to produce your own test again

The problem with oral compounds is they must first pass through the liver before entering the blood stream. All steroids pass through the liver and are eventually metabolized (producing the toxicity) but injectables do not have to undergo this extra pass before entering the blood.

Mikej22: Dunno if you already bought your Clomid, but Kessar is cheaper and 20mg kessar is as potent as 150mg clomid. thus making it much more cost effective to use as PCT.

Kessar and clomid is not the same thing guys. Kessar is used for the suppression of estrogen in breast cancer patients, that's why we get bitch tits when on test for too long. And Clomid, which promotes the complete hypothalamohypophysial testicular axis (which as understand it is basically: increasing the size of your eggs so you can produce enough of your own test.) I'm not an expert but this much I know.

vega5 wrote:

I'm not an expert but this much I know.

Then let me help extend your knowledge a little bit. structurally kessar and clomid are virtually identical. If I can get these silly pictures to upload I will show you. Both clomid and kessar are selective estrogen receptor modulators (SERMs). This means they both bind the estrogen receptor and stop estrogen from binding it. Steroid users use SERMs both to stop estrogen related side effects and to bring back testosterone production (correcting the HPTA). The way that SERMs increase testosterone levels is by tricking the body into thinking there is no estrogen (because the receptors are blocked). The body then reacts by producing LH to produce more testosterone for conversion to estrogen by aromatase.

Although they both perform the same function kessar binds the estrogen receptor much more potently than clomid, making it the better choice for both blocking estrogen related side effects, and for bringing back testosterone production (increasing testicle size). In fact studies show that 150mg clomid increases serum testosterone by 150%, while 20mg kessar does the same thing. Thus 20mg kessar is as effecive as 150mg clomid in raising testosterone levels during PCT.

Unfortunately today many steroid supplier would not like you to know this information because they can make much more money off marketing clomid for PCT. Although clomid was once important for PCT it is now far overshadowed by kessar!

That's why I said i'm no expert. But thanks for the usefull info.

Pleasure bro, I'm only trying to help.