TRT Gone haywire

Hi guys

A bit of help/direction here please.

I'm 45 years old and have been on TRT for a few years now, running test at 200mg/week for the last 18 months or so. I have cycled in between and will give some history below.

My test results in February this year. I haven't included lab ranges.
Total Test - 23.4 nmol
SHBG 20.2 nmol
Free Test 656.9 pmol - Target upper 700's
Estradiol 117 pmol (31pg/ml) - Target is 81 pmol OR 22pg/ml

My results this week.

Total Test - 14.2 nmol
SHBG 23.3 nmol
Free Test 348.9 pmol - On 200mg/week!
Estradiol 61 pmol - 16pg/ml
DHEA - first test - 13umo Range is 1.9 to 13.4 (I'm supplementing with 25mg DHEA daily)

I've only recently been feeling the effects of low test and my estrogen being out of kilter.
All I have done recently (three months ago) is 250iu Hcg 3 x week for 4 weeks ( I run Hcg every 3 months or so for 4 weeks) followed by a run of SARMS, stacking Cardarine and LGD. I've run test at 200mg/week throughout.

I planned the SARMS for 8 weeks but stopped after 4 weeks as I wasn't feeling good ( I know that's not scientific, but to me I was getting very irritable, libido was low, sleep badly interrupted and generally not interested in life much). I stopped and just continued with my usual testosterone, 200 mg/week. I didn't do a PCT as recovery wasn't really top of mind for me considering I'm running exogenous test constantly.

About 4 weeks ago I started adex at 0.25mg every second day, I was concerned about my estrogen levels being too high and I attributed the irritability and low libido to high estrogen.

Obviously the adex did it's job to the estrogen, which is now lower than I would like. So my issue is why has my Test dropped so dramatically, almost to pre TRT levels (280 pmol)? I really have not done much different. Could the SARMS have such an impact on exogenous testosterone? As I understand adex should positively impact test levels if anything.

My immediate solution is to stop the adex, up my test to 300mg/week and test again in 6 weeks. Any comments or other ideas, something I'm missing maybe? It would be appreciated.


Cheers

You metion your ranges only not the reference ranges.

Howzit bud, are you using pharm grade test

I'm keen to check what's going on here been on trt myself

Thanks RB

Only because I'm in range and, honestly, the reference ranges are subject to such debate and change across labs. Here they are though. From Ampath

DHEA S - 1.9 - 13.4
Total Test - 6.9 - 23.6
SHBG - 13.3 - 89.5
Free Test - 170 - 660 .
Oestradiol - <160

Hey Lobo

I originally started on pharma (100mg/ml) some time ago but eventually just moved to underground as it was getting a lot to inject taking 200mg/week.


I'm using LP now and honestly have used tehir products over the years and never been disappointed. I guess it could be a product issue but I really believe in their quality so I don't think so hey....

I'm not too clued up on the numbers with all this bud let's check what some of the other chap can see, otherwise if I was you I would switch back to pharm grade and get bloods done after a bit.

Lp only makes oral as far as I know so assume you meant something else, keep us posted

My mistake, PGW Testocyp 250, not LP, thanks.

Very strange, I'm on 250 mg of PGW test cypionate and my bloods came back at 1130 (range 250-900) so quite a bit over range....

With your SHBG and E2 low, I don't think you're converting. Main question, how are you feeling? I maintain that test results are a guide, how you feel is primary.

Just keep in mind that sometimes lab tests can go wrong and results sometimes are off. If in doubt, maybe just have a single retest of a marker?

I don't think the sarms have anything to do with your low test, I mean, your natural production of LH has stopped long ago and your testes are only reacting to the HCG... Maybe the HCG went bad? Any chance it was left out the fridge too long? Just thinking out loud. That would have reduced its potency, but still, to show sub 300 is really strange....

May just have been a bad batch of gear.

Thanks.
I’m not feeling great at all, irritable, no libido, very fatigued, so I’d say the symptoms match the test results. I don’t think its the hcg as I stopped that almost 2 months ago. I know how I should feel, I’ve been on the crest of the TRT wave and I’m nowhere near that which sucks. Maybe it was the gear like Morrgear suggested, or something else I’ve taken, maybe stress at work messing with my cortisol, who knows.

I’m going to run at 300/week for 6 weeks or so and drop any AI, I’ll see where it goes. Thanks for the comments.

HCG could only boost your test levels. If you are on exogenous Test your total test should be in proportion to what you are taking. Only your free test could be influenced by your SHBG. One thought, I may have missed it but how frequently are you pinning and when did you do the bloods in relation to the pin? If you are pinning once or week and the gear was switch to Test Prop (not saying it’s definately the case but it’s not uncommon for underground’s labs (as tested overseas) to switch once Esther for another when they run out or their raw supplier switches them out. If your Test Cyp is actually Test Prop and you are pinning once a week, and the bloods are at the end of the week, your levels will have dropped. Just a thought. I personally pin every day or second day regardless of the Esther in an effort to remove any yo-yo effect. I would rather pin often with less (using and insulin syringe ) than a large pin once or twice a week.

you can try switch over to 30mg of test prop subq daily. That will eliminate the need for an AI.

I understood the same re the hcg boosting test and estrogen levels. I pin twice a week, subq. I last pinned Monday morning and tested Thursday morning. I purposely did it then to see what my “low” level would be. My previous test was handled the same. But there shouldn’t be such a big variance.
I’m going to take yours and empires advice and pin daily for now.

Thanks again