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Sas wrote: I have buds running Nolva (20mg) from day 1 of their cycle straihgt through the cycle, and then clomid 7 days and again nolva for 3 weeks for pct.....
Kak idea or not ?
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Muscleaddict wrote:
Sas wrote: I have buds running Nolva (20mg) from day 1 of their cycle straihgt through the cycle, and then clomid 7 days and again nolva for 3 weeks for pct.....
Kak idea or not ?
Running nolva right through your cycle is old school and outdated. It's used to prevent gyno but is not as effective as an AI and running nolvadex for a few months has health risks as well. It is liver toxic and can cause eye problems as well as being a carcinogenic. Taking it long term drastically increases your chance of developing fatty liver disease. But note that side effects like these are only associated with long term use so using it for a month for PCT is not a problem or to help with tapering off letro/adex.
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Muscleaddict wrote: You've heard how after a steroid cycle your HTPA is shutdown (Hypothalamic-Pituitary-Testicular axis). All three, your hypothalamus, pituitary gland and testes need to recover after being shutdown and PCT drugs target all three. HCG takes care of the testes part and clomid/nolva the hypothalamus and pituitary.
Your brain's hypothalamus sends GNRH to your pituitary to stimulate LH production so that you can make testosterone. Enter Clomid. Clomid binds to receptors at the hypothalamus acting as a wakeup call to restart GNRH production after this process has been on pause during your AAS cycle. Then what Clomid does that Nolvadex sucks at is it resensitises your pituitary cells response to the GNRH hormone.
Then comes Nolvadex's role. Both Clomid and Nolva will stimulate the release of LH which in turn will stimulate testosterone production, but nolvadex is more effective at this. A study comparing the 2 found that 20mg Nolvadex increases LH and test production as much as 150mg Clomid does. They also both block your estrogen receptors but nolvadex is better at this as well. Clomid acts as both a mild estrogen and anto-estrogen.
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FatBoy wrote: I'm also suffering with poor libido despite following PCT 2 down to the T. Without hi jacking the thread, what body asthetic changes result from PCT? Would just being patient and waiting it out be an option to consider or should I just repeat full PCT?
Great post MA!!
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