Triptorelin

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11 Feb 2013 09:12 #133056 by MCJ
Triptorelin was created by MCJ
Anyone use this before and have bloods done to confirm? Been doing some research and almost seems too good to be true. MuscleAddict? Inja? Admin?

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11 Feb 2013 09:55 #133057 by Empire
Replied by Empire on topic Triptorelin
I read about this ages ago, the doc said something about it, I started a thread years ago on it and I think admin got a response from the doc saying its not as fantastic as studies made it out to be...triptotolin acetate or something along that spelling.

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11 Feb 2013 10:35 #133064 by MCJ
Replied by MCJ on topic Triptorelin
Ah ok thanx. Will do a search and have a look. Even though not as good as hyped up to be, Still wonder if its better, on or below par to conventional pct?

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11 Feb 2013 12:09 #133069 by Muscleaddict
Replied by Muscleaddict on topic Triptorelin
Real world results don't seem to match the hype. It definitely does work for some but yea, results vary. Considering that triptorelin is a GnRH analog just like HCG is an LH analog, and GnRH is what stimulates LH production in the pituitary, in theory it should be amazing for PCT but the mixed response that guys have gotten makes me wonder. But if you have a reliable source I would still recommend trying it out because I've seen a lot of guys on other forums say it's worked well. You might be one of the guys who responds well.

I don't see it being any better than doing HCG/nolva/clomid though which has a far better success rate anyway.
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11 Feb 2013 12:55 #133072 by admin
Replied by admin on topic Triptorelin
Doc:

Triptorelin, as far as my knowledge, is no longer available in South Africa. It has been replaced by the GnRH analogues Buserelin ( Suprefact by Sanofi), Goserelin (Zoladex by AstraZeneca) and Leuprorelin (Lucrin by Abbott Labs). Buserelin and Leuprorelin are indicated in the use of advanced prostatic cancer, where total suppression of testosterone is needed - hence the dosages range from 9,9 milligrams to 11,25milligrams - read medical "castration" levels. Zoladex is indicated for advanced breast cancer, also at high dosages.

I've known about the GnRH analogues for many years. So, why have I not used it as PCT? Simple answer - your HPT-axis is a very sensitive system. Once you have buggered it up, it won't rebound. I designed my PCT protocol specifically to hit the testicular level and NOT stimulate the HP-part of the axis directly. The latter is the most sensitive part of the axis. You have to be extremely careful of dosaging stimulating these sensitive glands directly. With my protocol, even if it takes longer than that "shortcut one-shot" everybody is always looking for, the HP -part is stimulated by physiological levels of hormone production from the testii. Then, also remember why I prefer Ovidrel above HCG. Ovidrel, being only the alpha-subunit of the HCG molecule, binds to three different receptors - FSH, LH and TSH. Why do I prefer to use the Clomids first? Studies have shown it to "prime" the testii for the first LH response. That initial testosterone response after the Clomid and first LH surge, will lead to high testosterone production, which will easily estrogenize. These high estrogen levels then again will suppress the HP-axis part - that's why tamoxifen is used to counter-act this estrogen production in the testii.

I prefer this protocol and not to use protocols of hormonal stimulation directly to the HP-axis. I leave this sophisticated stimulation to Endocrinologists that perform these interventions in a very controlled enviroment. And the average b/builder that injects himself at home, is definitely not the "controlled enviroment" I'm referring to here..

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