Injectable Carnitine

Hey Morgear. Any updates on your l-car use? Most info I've read suggests the injections should be done IV to increase the bio-availability, rather than just subq.

This study points out that it's effective orally too, without the need to use slin:

www.ncbi.nlm.nih.gov/pmc/articles/PMC3784205/

Sorry reply took so long, I seemed to have missed message. I am injecting IM, it's 2ml at a time so subq ain't an option. The main effect t I have seen is improved ability to stay lean while bulking. I increased calories over the last 12 weeks to the extent that I would have historically gained weight and BF to a greater degree than I have. The negative is pinning 2ml every day before training gets irritating specifically given that one is also pinning gear every few days. You feel like a pin cushion. I did load using insulin at 6iu per day for 2 weeks.

On the study and the oral option, it does work but to get the same levels in the muscle one needs a crap load of Lcar - in the study it was 1.38g

Thanks for the response Is there any evidence that IM or subq injection improves absorption over oral consumption? Most of the research I've come across only refer to IV vs oral. Most of the injectables I've seen are labelled as IV grade. Thought that was for a reason, i.e. it's supposed to be IV'd.

There's a huge difference in the absorption/bioavailability of IM vs oral. IM shots are still absorbed into the bloodstream, just at a slower rate than directly into the blood via IV. Oral bioavailability is extremely low, so you don't need a study to confirm that. Carnitine is not fragile like a peptide hormone so it's not going to degrade much before it hits the blood.

Thanks MA. My question wasn't solely based on the bioavailability, but also the absorption rate. There appears to be a small window after a carb spike/slin pin to shuttle the carnitine into the muscle.

I'm guessing the IV route was used rather than IM/SQ because it is the quickest and most reliable, while orally will leads to the slowest utilisation of lcar. IM is probably faster than oral, but I was curious if it was significant enough to justify pinning it vs taking larger scoops orally The study I linked to showed significant results using only 1.36g of lcar pd orally.

Not arguing at all. I just find the topic interesting.

I've been running it on training days 2ml IM pre workout and I'm really impressed with it. The same brand that was in Muscle Evolution