Some info on dasges so far.....
**A typical recommended dose of citrus aurantium is 100-150mg 2 to 3 times per day.
Many Citrus aurantium products are made from the juice and/or concentrated extracts of the peel
and are said to contain a fixed percentage of synephrine or total amines.
A typical recommended dosage of such products ranges from 100–150 mg two to three times daily.
However, these doses may be unsafe.
Because synephrine is but one small component of the Citrus aurantium fruit,
a standardized extract is recommended. A dose of 4-20 mg of synephrine per day is a typical dose found
in products providing 200-600 mg of a standardized citrus aurantium extract (3-6% synephrine).
The Chinese herb Zhi shi, which is the immature Bitter Orange (Citrus aurantium),
is used to manufacture Citrus aurantium extract. This herb, Zhi shi, has been used in Chinese medicine
for several centuries for a variety of purposes, including as a digestive aid,
generally in doses of 3 - 15 grams as a decoction, but sometimes in doses as high as 45 grams.
The herb contains about 0.8% of mixed alkaloids, with synephrine predominating
(the natural form of the alkaloid is l-synephrine), so the normal dose of 3 - 15 grams
would provide 24 - 120 mg of Citrus alkaloids per dose, with an intake of as much as 360 mg not being unusual.
There are no reports of side effects at these dosage levels. In addition to administering the herb itself as a
decoction, extracts are also administered by the intravenous route in the treatment of shock, in doses
equivalent to 10 - 40 grams (80 - 320 mg alkaloids).
Synthetic dl-synephrine is used therapeutically world-wide, often under the name oxedrine.
The recommended dosage is 100 - 150 mg three times daily, with a maximum daily intake of 600 mg.
At these dose levels the only reported side effects are rarely bradycardia
(slowing of the heart rate; ephedrine, the main constituent of the Ephedra alkaloids,
increases the heart rate) and exacerbation of narrow-angle glaucoma.
