Site Injections

What's everyones opinions on site injections? Since I have started pinning rear delts I can definitely see an inprovement in that area. Now its not major and I have taken swelling into account, but there is a difference. Maybe because its a smaller muscle. Doubt it will have much effect on bigger muscles like glutes and quads.

Rear delts are also the most painless site to pin. Was sceptical at first but it works like a dream.

There is no real local muscle growth from site injections other than the stretching of the fascia tissue by the oil which can assist growth slightly. Any quick size gained is from the oil and swelling. It is temporary.

Even if we injected 100% pure steroid with no ester attached there would no site growth because anabolic effects are systemic. The steroid hormones do cause growth by attaching to androgen receptors at the injection site and making them grow. That is broscience. Steroids cause growth systemically by increasing IGF1 production in the liver, increased nitrogen retention and protein synthesis, enhanced nutrient shuttling efficiency and all that complex crap.

I've tried this before as well in delts. I also noticed slight growth but it was temporary and if anything I benefited less than my normal glute shots because of the reduced bioavailability when injecting in to delts vs glutes.

"....reduced bioavailability when injecting in to delts vs glutes"

Care to explain this plz MA. Haven't heard that one before.

Ok. Just have to find the pdf's quick so I can be sure about the figures.

Muscleaddict wrote: Ok. Just have to find the pdf's quick so I can be sure about the figures.

Ok thanx man

Only found this one. Will look for the other study a bit later. When comparing 1ml Deca shot into glutes vs 1ml Deca shot into delts bioavailability was 73% vs 56%:



Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: effects of ester, injection site and injection volume

Twenty-three men were ran- domized into groups receiving nandrolone phenylpropionate or nandrolone decanoate injected into the gluteal muscle in 4 ml of arachis oil vehicle or nandrolone decanoate in 1 ml of arachis oil vehicle injected into either the gluteal or deltoid muscles.

Plasma nandrolone concentrations were influenced by different esters and injection sites, with higher and earlier peaks with the phenylpropionate ester, compared with the decanoate ester. After nandrolone decanoate injection, the highest bioavailability and peak nandrolone levels were observed with the 1-ml gluteal injection.

Plasma inhibin concentrations were also significantly influenced by injection volume and site, with the lowest nadir occurring after the nandrolone decanoate 1-ml gluteal injection. Thus, the bioavailability and physiological effects of a nandrolone ester in an oil vehicle are greatest when the ester is injected in a small (1 ml vs. 4 ml) volume and into the gluteal vs. deltoid muscle. We conclude that the side-chain ester and the injection site and volume influence the pharmacokinetics and pharmacodynamics of nandrolone esters in an oil vehicle in men.

The absolute bioavailability of nandrolone from i.m. injections of esters was significantly higher for nandrolone decanoate injected into gluteal muscle with a 1-ml volume (73%), compared with the other three groups (53–56%).

Reference: THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Vol. 281:93–102

That study was supported by Organon who manufacture Deca. It is a 10 page publication that doesn't miss a thing so it seems totally legit wrt the numbers.

Muscleaddict wrote: That study was supported by Organon who manufacture Deca. It is a 10 page publication that doesn't miss a thing so it seems totally legit wrt the numbers.

Interesting. So what happens when glute sites are saturated and need to pin elsewhere? U basically waisting gear?

Thx for the info MA. I still grow like a MothaF pinning delts. I have no option but to rotate pinning sites as i use prop esters.

However - i am going to give PGW long esters a shot soon... (1st long ester cycle in years...)

Seems like it MCJ . My guess would be that it's best to alternate between glutes and quads according to the data. What is also interesting is that it seems the less oil you inject per site, the more AAS is absorbed. Injecting 100mg of Deca in 4ml of oil was much less effective than 100mg of Deca in 1ml of oil. Blood serum levels of nandrolone were only 75% of those who injected the 100mg/1ml throughout the entire 32 day follow up after injections.

Oupa wrote: Thx for the info MA. I still grow like a MothaF pinning delts. I have no option but to rotate pinning sites as i use prop esters.

However - i am going to give PGW long esters a shot soon... (1st long ester cycle in years...)

Yeah this is just one of those things. At the end of the day none of use have noticed the difference but it's worth keeping in mind.