CJC-1295 DAC

Hey guys

I have been doing a little research on this peptide and am finding some contradicting info.

Some say to use 2mg once a week due to its long half life where others say twice a week and then again some say 20-30mcg per kg of bodyweight? Kind of confusing.

Would like to try this in a cycle sometime with igf1-lr3 and plain test or something similar. Maybe even with the GW-501516. Now I haven't done any research on this proposed cycle yet so don't even know if it would be viable. One step at a time and trying to understand the cjc first.

Also is there a difference between CJC-1295 DAC and CJC-1295? Seems like the DAC has the longer half life unless I understood it wrong and both are the same thing.

Anyone have any additional info to share? I have done a search and found a thread acidkidsa posted with some info so if someone could add to that as well plz.

Okay I can answer some of my own questions. Found some nice info.

The difference between cjc-1295 and cjc-1295 DAC is the half life. cjc-1295 has an active half life of about 30min where the DAC has a half life of 7-8 days which allows for once a week injections. So this also clears up the dosage issue as the split dosages would be related to the cjc-1295.

The cjc-1295 DAC seems to be the more potent peptide by far between the two due to its constant release of GH. Its also recommended not to use it for longer than 6 months as there seems to be insufficient research or long term data on how constant GH release will affect the pituitary gland.

Increasing the dosage of cjc-1295 DAC will lead to higher basal levels of GH and IGF-1 but this would also increase the risk of side effects such as water retension and carple tunnel which leads to numbness of the arm and hands. 4mg/week dosages seems to be the maximum dosage that bodybuilders use for positive affects on muscle mass and fat loss. Going over this dosage would result in tremendous lower back and calf pumps when doing cardio and weight training.

Taking all this into consideration I hope the DAC version is available rather than the short half life version as it would make things a lot easier, cheaper and simpler.

It seems the cjc-1295 DAC is by far the most potent peptide for overall muscle gain. A combination of ghrp-6 + cjc-1295 DAC + IGF1-LR3 would yield the best possible results for muscle gains.

Hey Bud! Here is a all you want to know about it. When you read about it on other forums they refer to a Mod GRF (1-29). This is CJC 1295 withou the DAC. The product currently available from LP. This is the one you want and you dose it with your GHRP of choice. The saturation dose is also the same.

www.datbtrue.co.uk/forums/showthread.php...should-I-use-and-why

ABC01 wrote: Hey Bud! Here is a all you want to know about it. When you read about it on other forums they refer to a Mod GRF (1-29). This is CJC 1295 withou the DAC. The product currently available from LP. This is the one you want and you dose it with your GHRP of choice. The saturation dose is also the same.

www.datbtrue.co.uk/forums/showthread.php...should-I-use-and-why

Thanx dude. I saw that link on a previous post when I done a search. I registered and waiting to be accepted. Just to be clear....the LP cjc is with the DAC?

It is without the DAC. The CJC 1295 with DAC causes GH bleed which is better to try and avoid. They have some good info on IGF 1 LR3 as well. You will find their dosing suggestion also a bit contradictory :whistle:

As far as my research suggest the longer half life of the DAC is more desirable and its for that reason that it causes GH "bleed". Also suggest that should not be used for longer than 6 months due to this exact reason. Also that the DAC is much more effective. Pity LP doesn't have the DAC. Not really interested in the cjc without the DAC

ABC.....what is the recommended dosage and frequency for the LP cjc without the DAC? I have basically just researched the DAC. I know it comes in 2mg/2ml vial.

Can't access that other site yet.

According to my research you dont want DAC because of the bleed. The bleed is caused because of the constant release of GH. Without the DAC the body releases the GH in more natural pulses with your bodies natural rythm. And if i'm correct the CJC without DAC has a long halflife as well. YOu take it with something like Huperzine A to lessen the effect that the negative feedback loop has onb rendering the GH useless.

Megusta wrote: According to my research you dont want DAC because of the bleed. The bleed is caused because of the constant release of GH. Without the DAC the body releases the GH in more natural pulses with your bodies natural rythm. And if i'm correct the CJC without DAC has a long halflife as well. YOu take it with something like Huperzine A to lessen the effect that the negative feedback loop has onb rendering the GH useless.

Without the DAC the half life is not long at all. Can't remember exactly but its like 30min or an hour or something. Hence the reason for 2 or 3 pins a DAY opposed to one pin a week. There is no conclusive evidence to suggest the GH "bleed" is bad for health as there is insufficient research on its long term use. That's why it states to take a break after 6 months. During the break the cjc without DAC can be used. You also do not need insulin spikes or any specific diet protocol when using the DAC where the other is very diet dependent in terms of insulin spikes, when not to eat what etc. The constant release of GH is actually desired as it promotes maximum results. DAC wins it hands down for me.

MCJ wrote: ABC.....what is the recommended dosage and frequency for the LP cjc without the DAC? I have basically just researched the DAC. I know it comes in 2mg/2ml vial.

Can't access that other site yet.

The saturation dosage is the same as the GHRP's which is 100mcg (or 1mcg/kg bodyweight). You pin this the same time you pin you GHRP. You can then play around with a high dosage of the one and low of the other. It opens up a entire diff world of possibilities. To avoid confusion that stick to 100mcg of each per shot

Great thread ... just what I was looking for!

Would it be sufficient to pin 1295 only once a day ... pinning 300mcg pre bed used with Ipam pinned simultaneously at same dosage to keep the somatostatin bound and have the pulse-released HGH get to work? Or perhaps pin 150 after work and another 150 pre-bed? The reason I'm asking this is that my Father is 61 and he has been complaining about exhaustion and fatigue a lot lately. I could also that things are changing and I had him do a blood panel. The results came back indicating that his Test is quite low ... he is producing less than 20% normal range. I am getting him on 100mg Enan/Wk, but figured that some Hygetropin would be good as well ... but then heard about 1295 and started researching it. I think it might be a good addition for him to be on permanently as opposed to Hygetropin seeing that it is not an exogenous hormone introduced into the body, but stimulation occurs for the body to release AND ustilise it's own HGH better.

He is still actively working everyday on a Platinum mine as a Fitter/Turner and has to move around the shafts and workshops a lot every day carrying his tools wherever he has to go and those in the know will agree that those toolboxes weigh quite a bit. He cannot have the tiredness/lethargy associated with a proper dosage of 1295 (or is it the Ipam causing the lethargy?) while he is at work, so skipping the morning pin would probably assit with that.

Perhaps pinning 100mcg after work and then another 100mcg pre-bed would also be more beneficial than nothing at all?

I wish I was more familiar with these compounds!

I would not use CJC 1295 alone. According to what i have seen during my reading, the spike in GH is almost non existing compared to Any GHRP or GHRP + CJC 1295 without the DAC. To get back to your question: You could pin the GHRP 2 x per day and only add the CJC 1295 to your pre bed shot.

So the Blue indicates when the GHRP actually spikes the release of HGH? The green is the 'near to not worth mentioning' spike the 1295 induces and the red is the effect of injecting actual exogenous HGH? Is the advantage, based onthis then, of using 1295 with a GHRP then ... what? The 1 small spike per day more than GHRP? So then it would be more beneficial to run CJC-1295+Ipam as I figured it would be? I know than the Ipam prevents the somatostatin from neutralizing the released HGH and the 1295 cuased pulsed releases of HGH ... but I was not aware that Ipam actually causes spikes in HGH release? Nice ... so the unison in using Ipam+1295 is a winning recipe for sure then?

What is CJC-1295, CJC-1293, GRF(1-29), Sermorelin and modified GRF(1-29)?


In short they are all forms of GHRH (Growth Hormone Releasing Hormone).


What are GHRP-6, GHRP-2, Ipamorelin, Hexarelin?


In short they are all forms of GHRPs (Growth Hormone Releasing Peptides, Ghrelin-mimetics)

Ghrelin is a hunger derived gut-hormone. It is capable of making its way to the pituitary where the GH releasing cells (somatotrophs) reside. Just like GHRH & Somatostatin it also can contact the cell. When it does it reduces Somatostatins effect. Ghrelin increases GH release. It does this in several ways -by encouraging the brain to release more GHRH, amplifying the effect of GHRH when it gets to the somatotroph, benefiting from GHRH being at the cell to amplify Ghrelin's own effect which is in part an increase in GH release and countering Somatostatin's stoppage effect at the cell.


In fact Ghrelin can cause GH release all by itself even if Somatostatin is around. But Ghrelin makes the environment safe for GHRH to act and if GHRH acts when Ghrelin is there the result is what is called a synergistic GH release. Synergy means the amount is larger then each could have produced on its own. If Ghrelin would cause 5 units to be released and GHRH 2 units when you put them together synergy means the result is more then additive (5 + 2). The synergistic result may be 15 units. Why does synergy happen? GHRH and GHRP help each other... they make each other stronger.

Awesome ... So the desired effect af pulse-based release and then the ability to actually release by using the 2 compounds together is pure synergy!? Thanks Bud!

I have been curious about the DAC(drug affinity complex) as well. The whole bleed vs pulse debate. I did read somewhere that women have less of pulse and more of a bleed type scenario going on. Not sure if anyone can confirm it?

MCJ have you tried running 1295 DAC? If yes, how did you use it? Alone?

Thanks,
Toshiro

I know of someone that finished a cycle a few weeks ago with awesome results with ipamorelin/cjc-1295/ghrp-2.
Rather don’t do CJC-1295 on its own. Also its better to use ipamorelin than ghrp-6

I have read of good results from CJC1295 and Imparelin. No mention in the things I read though if it was DAC or not.

I would assume you could use the DAC version once per week. Then just pin the Imparelin (or whatever GHRP or Combo of GHRP's) you want for however many times you need for your goals. For example assuming a male candidate:


Example A.
CJC1295 DAC 2mg x1 per week.
Imparelin 100mcg 3x per day x 7 days a week (more aggressive usage to simulate GH pulses)

or

Example B.
CJC1295 DAC 2mg x1 per week.
Imparelin 100mcg once per day x 7 days a week (more anti-aging/general health usage)


Otherwise you have to pin the non DAC versions of a GHRH with it each time right? Does this make sense?

Thanks,
Toshiro