T3 effects on IGF???

ohk here we go

i was reading up and doing a bit of research on the net on the test+slin+gh+t3 combo thats soooo sought after in bodybuilding! lets just take average dosages of all those compounds in a nice lean gan cycle for an offseason peroid with all the right protocols etc...but m question to you guys is this

logically high dosages of t3 would make u able to consume a huge amount of calories per day which in return would drive me to think that would obviousy have a huge impact on growth with all the protein synth u get from t3 and all the other components aswell as less fat gain?? right.. logically yes but then i found something interesting...

high levels of t3 causes a rise in igf binding protein like shbg or albumen for test, can anyone clarify this? how of a negetive impact would this have with your gh as this is the main pathway it creates new fibers and enlargement...and ofcourse this would be affected wth the use of slin coz the igf is bound now??

this really boggles me?? plz plz help

thnx in advance

oh and i forget to ask

how much of a negetive impact would this have on the muscle building potential of such a cycle, the binding of igf ofcourse and to how much of a degree would this impact gains?? coz logicall it doenst matter how much igf is increase due to AS if it is bound you are screwed??

No no no, T3 causes protein catabolism (muscle wasting). That is why it must only be taken in combination with anabolics. T3(triiodothyronine) together with T4 (thyroxine) are the thyroid hormones that regulate metabolism so increased levels of T3 have a direct effect on protein, fat and carbohydrate synthesis.

GH can limit the production of T4 which in turn gets converted to T3. Therefore there is a synergistic relationship between T3 and HGH and I personally always combine GH with a T3/T4 combo (Diotroxin).

There is a very good article written by Mark Stent on this:
www.steroid.com/sitearticles/Hormones/Gr...Anabolic-Synergy.php

yes yes i do understand the whole proces of metabolism wth the thyroid meds increasing metabolism of ALL calories and in combination with AS this can be very synergistic'

my question however is in regards to usng all the compounds together namely test+gh+slin+t3

how much of a negative effect would the binding of the igf due to t3 have on muscle building in such a stack?? or can this be negated in some way or is this already negated due to the compounds used?? hgh gets metabolised to igf in the liver when injected and when slin is used it pushes the nutrients in and also closes the so called gap of the igf towards muscle. im just curious as to this would defnitely be impacted in a huge way coz if the igf is bound that is the actual way of transport then in combination with slin

sorry if im confuzing hope this clears it up

I'm not sure if I'm understanding you corretly but this is how I understand it: IGF is a hormone produced in the liver that is responsible for nitrogen retention and protein synthesis. Its release is directly triggered by the presence of GH so the two are highly inter-related. Testosterone and Insulin are synergistic to GH so would also elevate lvels of IGF in muscle cells causing an increase in lean body mass. The incorporation of T3 in the mix is not going to negate the effect of IGF. If anything it will stimulate GH production allowing the release of more IGF. I don't think you must look at the effects of each compound as individual process. Instead they all work in synergy and are inter-related with eachother.

yup and thats exactly why its so amazing

but look here

testosterone has shbg that binds to it, the bodys natural response of too much test to regulate it

now that goes the same with igf as i understand it. high t3 dosages causes a rise in igf binding protein rendering it inactive just like shbg for test

and i would really like to know i anyone can contribute to this?? and is there any way of negating this binding of igf?

hope this is better??

Ok, now I think I can understand what you were orignially asking. I don't have an in-depth knowledge on the subjct but I know there are different types of IGF that can be used in combination with T3, GH etc. The one type called LR3 IGF-1 can be used with higher doses of T3 because LR3 binds poorly to IGF-1 binding protein, and yields an increased anabolic effect.

Hope this helps.

ah awesome didnt know that about lr3 but what im refering to is the igf release caused by the growth hormone...is that release of igf bound due to the t3 or not? coz that would obviously cause your growth to be nothing more than just an expensive fat burner

Many would say that low doses of HGH (1iu to 4iu /day) is just an expensive fat burner. To answer your question, HGH causes a rise in IGF and an excess amount of T3 causes a rise in IGF-binding protein. That is why T3 levels must be carefully monitored with HGH (or IGF-LR3 can be used to allow higher levels of T3)

Sorry I'm late for a meeting but I'll put more thought into this when I get back.

STUARTF wrote: No no no, T3 causes protein catabolism (muscle wasting). That is why it must only be taken in combination with anabolics. T3(triiodothyronine) together with T4 (thyroxine) are the thyroid hormones that regulate metabolism so increased levels of T3 have a direct effect on protein, fat and carbohydrate synthesis.

GH can limit the production of T4 which in turn gets converted to T3. Therefore there is a synergistic relationship between T3 and HGH and I personally always combine GH with a T3/T4 combo (Diotroxin).

There is a very good article written by Mark Stent on this:
www.steroid.com/sitearticles/Hormones/Gr...Anabolic-Synergy.php

Nice article! It concludes that T4 should be used instead of T3 while on GH. Before the FBI hit Anthony Roberts (lol!), he was convinced by certain James Daemon (Phd)to come to a similar conclusion: "If you’ve been using GH without T4, you’ve been wasting half your money – and if you’ve been using it with T3 , you’ve been wasting your time. Start using T4 with your GH, and you’ll finally be getting the full results from your investment." ( forums.steroid.com/showthread.php?253351...n-Ph.D.#.T0dBvIfxpKk ) I just wonder if anyone out there has confirmed all this theory during their course?

salaza wrote:

STUARTF wrote: No no no, T3 causes protein catabolism (muscle wasting). That is why it must only be taken in combination with anabolics. T3(triiodothyronine) together with T4 (thyroxine) are the thyroid hormones that regulate metabolism so increased levels of T3 have a direct effect on protein, fat and carbohydrate synthesis.

GH can limit the production of T4 which in turn gets converted to T3. Therefore there is a synergistic relationship between T3 and HGH and I personally always combine GH with a T3/T4 combo (Diotroxin).

There is a very good article written by Mark Stent on this:
www.steroid.com/sitearticles/Hormones/Gr...Anabolic-Synergy.php

Nice article! It concludes that T4 should be used instead of T3 while on GH. Before the FBI hit Anthony Roberts (lol!), he was convinced by certain James Daemon (Phd)to come to a similar conclusion: "If you’ve been using GH without T4, you’ve been wasting half your money – and if you’ve been using it with T3 , you’ve been wasting your time. Start using T4 with your GH, and you’ll finally be getting the full results from your investment." ( forums.steroid.com/showthread.php?253351...n-Ph.D.#.T0dBvIfxpKk ) I just wonder if anyone out there has confirmed all this theory during their course?

I agree with that article by Mark Stent 100% and the article by Anthony Roberts comes to the exact same conclusion which is great. Its also good to know that its been backed up by medical professionals like Dr Daemon. I will only ever use T4 or a T3/T4 combo with HGH. To be honest I have never used GH without diotroxin so I wouldn't know the difference.

Like the article says... "if you do If you’ve been using GH without T4, you’ve been wasting half your money – and if you’ve been using it with T3 , you’ve been wasting your time. Start using T4 with your GH, and you’ll finally be getting the full results from your investment."