Any of you guys heard of this?
Its a myostatin blocker, there was a writeup on muscular development about it,read below
New abstract presented at:
American Society for Biochemistry and Molecular Biology
www.asbmb.org
Post Translational Modifications Meeting
October 23-26, 2008
Granlibakken Conference Center and Lodge, Lake Tahoe
Abstract Poster Presentation
Effect of Debulked Fertile Egg Yolk Ingestion On Serum Myostatin Levels. Reviewed and accepted for poster presentation at the 2008 Conference on Post-Translational Modification: Detection and Physiological Evaluation for the American Society for Biochemistry and Molecular Biology; Category: Unusual Modifications; Poster 5; Abstract 10; October 24, 2008.
EFFECT OF DEBULKED FERTILE EGG YOLK INGESTION ON SERUM
MYOSTATIN LEVELS
Standard but properly handled fertile egg yolk powder contains significant concentrations of follistatin and other naturally occurring co-factors. We know that this source when properly processed to preserve active follistatin, increased serum follistatin and decreased serum myostatin when orally ingested in a relatively high amount. The limiting factor was the bulk of the product (mainly accounted for by water and lipids) as well as the still relatively large serving size. In an effort to reduce the bulk of the product while preserving naturally occurring follistatin, a newer centrifuged debulked version of the product (Folstaxan™) was created. Using this product at a significantly lower serving size we theorized that as little as 20grams of orally ingested product could still suppress myostatin. This study was undertaken to test this hypothesis. Seven (7) male subjects were recruited. Follistatin-rich, debulked fertile egg yolk powder properly handled to preserve active follistatin (Folstaxan™) was obtained (Celldyne Biopharma, San Antonio, TX). After initial blood draw and providing oral Folstaxan™ at a single 20 gram serving size, serum myostatin levels were qualitatively and quantitatively measured as an indicator of pharmacokinetic activity. Testing utilized a purchased myostatin standard for verification. Confirmations were run by ELISA and quantitations by Liquid Chromatography Tandem Mass Spectrometer with third degree fragmentation (Expertox, Deer Park, TX). Results showed an average baseline myostatin level of 27pg/ml; 12 hours after Folstaxan™ ingestion, average serum myostatin declined to 24.43pg/ml; Average serum myostatin continued to decline with a 24 hour level of 23.86pg/ml. These results indicate that a debulked fertile egg yolk powder properly handled to preserve active follistatin, when orally ingested at only a single 20 gram serving size, can in fact still produce a major reduction in serum myostatin.
Discussion of Study (non poster)
Five out of seven subjects responded favorably (had a significant reduction in myostatin) to the product. One had no change in myostatin level, and one had an increase in myostatin over at 12 hours, and a decrease at 24. There may have been confounds with these two outliers regarding compliance. One subject reported loose bowels. This was the only adverse event reported.
In responders, there was a much higher average reduction of myostatin levels. The average reduction in myostatin for responders at 12 hours was 15%. The average reduction in myostatin for responders at 24 hours was 22%. Studies have shown that a 20% reduction in myostatin levels will lead to significant increase in muscle mass.
Folstaxan is available for purchase at
www.folstaxan.com
and delivery is within 10 to 15 business days.inside USA
