Official peptide thread

howzit guys...

ok so i know myself am VERY VERY curious about all these new peptides out, and im sure all of you guys are too, so i thought one thread would be cool to get in all the info relating these, namely being Ipamorelin, Hexarelin and CJC-1295 aswell as GW-501516 if you like.

i have been making a collection of research on each and will post soon,

if you guys have ANY info regarding the above, you input will be greatly appreciated as im keen to learn more about these peptides,

peace out

howzit PP

hope all is well. nice thread by the way im also very interested in learning more about these peptides so ill be monitoring this thread closely.

so far i'm most interested in Ipamorelin. was looking into ghrp-6 but Ipamorelin is just as effective and doesnt create prolactin or cortisol at a higher doses.

my plan is to start during PCT, so in a few weeks.

you have any info on Ipamorelin you can post?

thanx bud

howzit bud! i was also highly interested in it, looks amazing, but want to do alot more research, the only thing i have found on ipamorelin, (bear in mind i only looked for about 10min before opening this thread) is the following, off elitefitness

'Ipamorelin is a fascinating new muscle building discovery that is getting a lot of attention in the bodybuilding world. Like the GHRP-6 peptide (growth hormone releasing hexapeptide), it is a synthetic peptide that has powerful Growth Hormone releasing properties. And these GH releasing properties are what is of interest to athletes and bodybuilders since they can make a tremendous difference in the amount of muscle you can grow and how quickly you burn fat. Both Ipamorelin and GHRP-6 as well as numerous other peptides and research chemicals can be found at PurchasePeptides.com.

Whereas GHRP-6 is a hexapeptide, Ipamorelin is a penta-peptide. (Aib-His-D-2-Nal-D- Phe-Lys-NH2) And, the strength it displays may very well make regular old Growth Hormone (GH) obsolete. But what athletes and bodybuilders really want to know is what is this wonder peptide capable of doing, how is it used, and how does it compare to the other GHRP peptides?

Athletes are taking Ipamorelin in a 200mcg -300mcg dosage, two or three times daily, using a tiny insulin needle to inject. They usually start with the lower dose since side effects can include headaches or what feels like a head-rush. Ipamorelin can be taken at anytime but taking it about 30-45 minutes before a workout would seem ideal because of the pulse in Growth Hormone (GH) it creates allowing for maximum growth.

Studies on the effects of Ipamorelin on bone growth, body weight, and GH release showed some interesting conclusions.

In one experiment, various doses were administered over the course of 15 days to test the group's reactions.

There was a distinct and dose-dependent effect on body weight gain however, the treatment group did not show a change in total IGF-I levels. Nor did the treatment group produce serum markers of bone development. For example, the number of cells in the wide portion of the tibia (the shinbone) did not change significantly. This is a good thing because it suggests muscle growth with less potential for deformity of bone or cartilage.

The reaction of the pituitary to an aggressive i.v. dose of Ipamorelin showed that plasma GH levels were notably reduced whereas they were unchanged after a comparable dose of GHRH. This is actually a good thing as it suggests that Ipamorelin may not decrease your body's natural GH production - further demonstrating that Ipamorelin is a selective GH releaser.

Unlike GHRP-6, Ipamorelin does not induce hunger making it advantageous to those on a restricted calorie diet. And obviously, Ipamorelin's side-effects are enhanced when combined with anabolic steroids since they too influence Growth Hormone/Insulin Growth Factor release and production.

In another study in rats, Ipamorelin released GH from rat pituitary cells as effectively as GHRP-6.

Another document states that in healthy swine, Ipamorelin released GH with a consistency that is very comparable to GHRP-6. Also noteworthy was that none of the GH releasers tested affected FSH, LH, PRL or TSH blood serum plasma levels.

Ipamorelin in theory may increase Acetylchloine or Cortisol when used in higher dosages. However, and increase in Acetylchloine or Cortisol is even more likely with GHRP-2 and GHRP-6. In fact, in the case of Ipamorelin, there was little to no rise in Acetylcholine and Cortisol blood plasma levels even at injections more than 200 times higher than the effective dosage for comparable GH release.

This clearly proves that Ipamorelin is the first successful GHRP receptor agonist or chemical that binds to a receptor of a cell and triggers a response by that cell with a specific selectivity for the promotion of GH release by itself.

Another advantage to Ipamorelin is that it doesn't cause sudden spikes in prolactin or cortisol as does GHRP-2 and GHRP-6. Ipamorelin is slower in its delivery unlike GHRP's which spike GH levels at a more rapid rate. The slower release is more natural and has a more sustained effect.

All in all it looks as if Ipamorelin is the new wave in GH releasing peptides. It appear to be more potent, longer lasting and potentially safer to use in the long run. More studies are being conducted all the time but as it stands, Ipamorelin looks like a serious contender in the arsenal of anabolic advancement'.

i saw many other threads that ill research just now and post up! hope this helps bud

thanks bro that helps a lot. +1

I reckon I'm going to go this route after my next cycle. Thanks PP +1

rvp01 wrote: thanks bro that helps a lot. +1

shot bud, i found a nice one on a brief description and dosing..

Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Purity: >99.5%

Description: Ipamorelin is a type of Growth Hormone Releasing Peptide, similar to GHRP-6. As the name suggests, the product works by stimulating the body to release more Human Growth Hormone (HGH) and IGF-1. HGH and IGF-1 levels decline rapidly as one gets older, and it is this decline which is thought to be responsible for the aging process. Besides a much lower cost, Ipamorelin offers another distinct advantage over HGH injections as it does not shut down the body’s natural production of this hormone, it just enhances it.

Compared to GHRP-6 and GHRP-2, Ipamorelin is more attractive because it is shown to be equally as efficient at the same dosage, but with the added benefits that it does not raise negative hormones such as cortisol (responsible for stress and muscle loss) and prolactin (responsible for sexual side effects, water retention and breast growth in some males).

Useful For: Bodybuilders looking to gain muscle; ordinary people looking to lose fat; older persons looking for anti-aging benefits.

Storage: Vials are freeze-dried and therefore will remain stable at room temperature for 1-2 months. However, for long term storage they should be kept a 2-8 degrees celcius (refrigerator temperature), where they will remain stable for up to 18 months in powder form. Once mixed with mixing solution, vials should be stored in the refrigerator and not left at room temperature. NOTE: Do not mix up all your vials at once. You should only mix up 1 (one) vial at a time and leave the rest in powder form until you are ready to use the next vial.

Amount of Water to Mix: You can mix 1ml (1cc or 100 units), 2ml (2cc or 200 units), or 3ml (3cc or 300 units) of sterile water, sterile saline (0.09nacl) or bacteriostatic water. The amount of water you mix makes no difference to the products effectiveness. The only thing that will change with the differing amounts of water is the amount you have to inject to get a certain dosage. For ease of dosing, we recommend mixing 1ml of water per vial (unless you have difficulty dissolving the peptide). Note: If the product does not dissolve into 1ml of water within a few minutes, do not shake the vial, but instead try adding another 1ml or 2ml of water and leaving the vial to settle for 24 hours in the refrigerator.

Dosage: Taken 1-3 times per day (once a day for anti-aging and 2-3 times for fat loss and muscle building). Males & Females = 100mcg (0.05ml or “5” units on the Insulin Syringe if you have used 1ml for mixing, 0.10ml or “10” units if you have used 2ml of water for mixing and 0.15ml or “15” units if you have used 3ml of water for mixing).

Number of Dosages Per Vial: 20 x 100mcg dosages.

When to Take: Must be taken on an empty stomach – this means at least 2 hours since your last ingestion of food or beverage containing calories (water and diet drinks are okay). And also waiting at least 30 minutes after your injection before consuming anything containing calories. If this measure is not followed then your injection may be less effective. Note: Optimal times to inject are therefore either one or all of the following: first thing in the morning, pre-workout and before bed.

How to Take: By subcutaneous injection into fat (stomach, thigh or buttock) or intramuscularly (bicep or shoulder) with an insulin syringe. Other peptides can be mixed in the same syringe and injected at the same time.

Possible Benefits: Fat loss, muscle gain, increased strength, improved skin tone, better sleep, more energy, stronger bones and connective tissues.

Possible Side Effects: Tiredness, increased hunger, water retention, tingling in hands and feet.

Best Combined With:CJC-1295 DAC or Modified GRF 1-29

for a FULL on scientific write up (i dont understand a word :pinch: ) here is a link, could be highly useful to come of the seniors etc.

www.eje-online.org/content/139/5/552.full.pdf

its dam interesting, i just cant make sense of half the terms they use

you the man bro

Can you use them together, will they work in synergy?

so a 2ml vail will last me 20days id i use it once a day(anti aging dose) and 10 days if i do two doses(bodybuilding and fat loss) a day?

ModGRF(1-29) is what you want.CJC-1295 and CJC-1293 ARE NOT ModGRF(1-29). Some companies will claim that CJC-1295 W/O DAC is the same as ModGRF(1-29) and it is technically but its the wrong name. To give an example its like me calling boldenone by the name unmethylated-methandrostenolone (unmethylated dianabol), the point I am trying to get across is that the name CJC-1295 w/o DAC is not a real name. Think of calling H20 DiHydrogen Oxide, its known as water not dihydrogen oxide.

CJC-1295 and CJC-1293 are not Mod-GRF(1-29) though. CJC-1295 has way too long a half-life/effective life and is not what we want. CJC-1293 is also undesirable but for other reasons.

You must use a GHRP in conjunction with GHRH to guarantee the release of GH. It's synergy effect is much greater together than alone. Try using 100mcg Ipamoreline & Mod Grf 29 - 3 times a day...pre-bed...post workout...mid of the night, or, first thing in the morning.

extract from T-nation

www.ExtremePeptide.com
best site ever to read all about peptides...

Megusta wrote: You must use a GHRP in conjunction with GHRH to guarantee the release of GH. It's synergy effect is much greater together than alone. Try using 100mcg Ipamoreline & Mod Grf 29 - 3 times a day...pre-bed...post workout...mid of the night, or, first thing in the morning.

^I'll bump this info in case anyone missed this. The greater synergy of using them together makes stacking rather than using just ipamorelin or another GHRP alone a no brainer.

Do not use a GHRH (CJC1295/MOD GRF29) alone, because there will NO growth hormone release if you happen to have elevated somatostatin (a growth hormone inhibiting hormone) levels when you inject. There is no way of being sure when somatostatin is elevated, so by injecting just a GHRH you are taking a gamble whether it is going to work each time. When stacked with ipamorelin (or another GHRP) you can guarantee effective growth hormone release every time, whether somatostatin is evelated or not.

I'm also new to GHRH's/GHRP's but I'm amped :woohoo: to start. I'll be doing 300mcg/day (3 shots) of ipamorelin & CJC1295 w/o DAC starting next month, and will continue for a few months and then reassess.

PoisonedPulse wrote: for a FULL on scientific write up (i dont understand a word :pinch: ) here is a link, could be highly useful to come of the seniors etc.

www.eje-online.org/content/139/5/552.full.pdf

its dam interesting, i just cant make sense of half the terms they use

Thanks for the link bud +1.

@ muscle addict

How many vails of each ipamorelin and cjc/mod grf would i need for a month/4weeks @ 300mcg/day? I understand they come in 2ml vails.

tnx

Muscleaddict wrote:

PoisonedPulse wrote: for a FULL on scientific write up (i dont understand a word :pinch: ) here is a link, could be highly useful to come of the seniors etc.

www.eje-online.org/content/139/5/552.full.pdf

its dam interesting, i just cant make sense of half the terms they use

Thanks for the link bud +1.

pleasure bud, first person i thought about when i saw all the science stuff was like muscleaddict will be right at home here haha hope it serves you well.

as for your stack of ipamorelin & CJC1295 w/o DAC - would you kindly track progress for us? as its the same combonatuion that caught my eye, will be much appreciated.

Hopefully i will be receiving my Ipamorelin tomorrow. I will start off at 100mcg every evening before bed for a week. Then i will add a aditional dosage pre workout and after 1 month i will add CJC 1295 without DAC and run that for couple of months.
Im currently in PCT and have read that nolvadex actually has a blunting effect on GH release. This makes the addition of Ipamorelin in PCT even more valuable

Megusta wrote: @ muscle addict

How many vails of each ipamorelin and cjc/mod grf would i need for a month/4weeks @ 300mcg/day? I understand they come in 2ml vails.

tnx

You'll need just over 1 vial per week. 300mcg/day x7 days = 2.1mg, and you'd need to be on it for a few months to really see the benefits.

PoisonedPulse wrote: as for your stack of ipamorelin & CJC1295 w/o DAC - would you kindly track progress for us? as its the same combonatuion that caught my eye, will be much appreciated.

Will do but I'll be on other stuff as well so my assessment might not be dead on accurate.

Muscleaddict wrote:

Megusta wrote: @ muscle addict

How many vails of each ipamorelin and cjc/mod grf would i need for a month/4weeks @ 300mcg/day? I understand they come in 2ml vails.

tnx

You'll need just over 1 vial per week. 300mcg/day x7 days = 2.1mg, and you'd need to be on it for a few months to really see the benefits.

PoisonedPulse wrote: as for your stack of ipamorelin & CJC1295 w/o DAC - would you kindly track progress for us? as its the same combonatuion that caught my eye, will be much appreciated.

Will do but I'll be on other stuff as well so my assessment might not be dead on accurate.

i know you dont have experience yet, but do you think 200mcg/day of each will work for muscle and fat loss?

General well being, better sleep and recovery (not from injury) will be seen at a single dosage of 100mcg pre bed

You can start seeing recovery from injury and some fat loss from 2 x 100mcg per day over time

It could have a bodysculpting effect and good recovery with the added fatloss from injecting 100mcg 3 times or more per day. You can do as much as 6 x 100mcg per day if you really want to.

Combining a GHRP and CJC 1295 (without DAC preferably) has a exponential effect. Its like 2 + 2 = 10 type of thing.

This is the short of some of what i have read on the topic

Megusta wrote: i know you dont have experience yet, but do you think 200mcg/day of each will work for muscle and fat loss?

I'll keep my opinions short since I haven't tried it yet. But even at 300mcg/day lean muscle gain is very slow so 200mcg is probably the lowest one should go, but rather up it to 300mcg. Just like there is not much point in running HGH for only a month at 3iu, if you're planning on only running it for a month then honestly don't even bother. Hey who wouldn't rather use 200mcg if it works and save some cash, but what's the point if it might be disappointing. I've done a a fair amount of reading and people seem to agree on 300mcg/day as the sweet spot if you want noticeable lean muscle gains along with the fat loss and anti aging benefits that a lower dose might be ok for. Results are SLOW so I'd prefer to do a bit more than the minimum.

I do 500mcg GHRP-5 daily....5 shots a day :pinch:

Good stuff!

Im looking fuller and strength is up, but keep in mind im in week 4 of my cyp cycle no oral kicker so it might be the cyp, but ya....

EDIT : GHRP-6 eidolon sorry! :blush:

Hey Lads

Nice thread, I think were all interested in this. I no none of us have any experience YET but from
What's you've read. How do you think gw-501516 compares to GHRP and cjc1297..?

I'm thinking of hanging on for GW-

gorilla wrote: I do 500mcg GHRP-5 daily....5 shots a day :pinch:

Good stuff!

Im looking fuller and strength is up, but keep in mind im in week 4 of my cyp cycle no oral kicker so it might be the cyp, but ya....

GHRP-5 or 6?

Ian79 wrote: Hey Lads

Nice thread, I think were all interested in this. I no none of us have any experience YET but from
What's you've read. How do you think gw-501516 compares to GHRP and cjc1297..?

I'm thinking of hanging on for GW-

I see them as being in completely different classes to be honest. The GHRP and GHRH's geared towards GH release and all the added benefists it brings while GW 501516 geared towards fatburning with a side effect being increased endurence and maybe added muscle mass.