MK-677 from Liquid-Pharma

MK-677, also called Ibutamoren, MK-0677 or L-163,191 will become available soon and I'm hearing some really good things about this chemical. I don't have personal experience with this drug and I've not yet read scientific studies on it, but here is the bro-science I've received from a friend regarding it's usage and what to expect:

MK-677 is an oral and can be taken once per day preferably at night because it may cause lethargy and increased appetite. Water retention is another side-effect experienced in the first 3-4 weeks. The water retention can be controlled with diuretics. Dosage is from 15mg to 30mg daily but those who did the 30mg daily are the ones that got the worst water retention and those who started at 15mg daily had less sides. Start at 15mg daily for a month then go to 30mg daily once the negative sides have subsided. People report full muscles, strength gain, fat loss (after the break-in period), healthy sleep and recovery.

Good day, read a couple of studies on the product, the studies are credable, but a little concerning as some of them were done over 12 - 24 months only. Strong cons for the product.............one pro con regarding the negative loop feedback on dopamine over prolonged use is concerning.
I would like to give it try...........price would be a definite factor as the product is designed for prolonged use for effective results.
Regards

I'll do some research and when it comes to dopamine I have enough tricks up my sleeves not to have that as a concern what so ever, but until I have spent time studying this compound I'll leave it there.

Yes please

Keen to give it a try: here is the conclusion from a study listed on pubmed:
CONCLUSION:
Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated. Long-term functional and, ultimately, pharmacoeconomic, studies in elderly persons are indicated.

Just take my money monthly...

@Pump

care to share some of those dopamine information? except using something like dostinex or caber

I was thinking more along the lines of Wellbutrin, but even clonidine or something similar that targets the b2a receptor might do the trick, but I'm not ready to write my findings yet, as I am not convinced there is even a problem.

I see a SARM, I buy it.

But seriously though, very interested in 677. Seems LP is the only one making SARMs, will try it if I can get some and report back

I'm currently on Dopaquel @300mg every night before bed ,it is a mood stabilizer and also got to do with dopamine levels ,not exactly sure because psychiatrist prescribed it long ago, but it most def stabilizes my mood ,without it i feel like a whimp.So i'm thinking it must stabilize dopamine levels too.

Havoc14 wrote: I'm currently on Dopaquel @300mg every night before bed ,it is a mood stabilizer and also got to do with dopamine levels ,not exactly sure because psychiatrist prescribed it long ago, but it most def stabilizes my mood ,without it i feel like a whimp.So i'm thinking it must stabilize dopamine levels too.

People know it better as seroquel. It's an antipsychotic, not exactly the right med for the job, in your case as a mood stabilizer / someone recovering from addiction / bipolar / depression and and and can work.

You're right 00pump it was stress and depression.

Was going through a lot of stress and feeling low. Doc did bloods, all came back clear. He put me on serdep 50mg. It's a very mild anti depressant. But more of a mood stabilizer. First 2 weeks was abit rough. But since then. I feel absolutely great. Mood is very stable and I handle stress much better.

This feels like chill pills .................. to soon to tell but will keep u all posted.

What dose are ya'll gonna be running mk at?

Oupa wrote: This feels like chill pills .................. to soon to tell but will keep u all posted.

Any changes in BP due to water retention ?

Feels like it, will measure over the next few days. Very very vascular.

DruOmedra wrote: What dose are ya'll gonna be running mk at?

15mg a day

How many pills are there in a container?

30 in the container so 1 bottle would last a month

I think it is worth taking 2 caps a day. I will give it a try and give feedback.

My blood pressure was little to high for my liking on 2 caps, but all seems good now and i will go back up to 30mg

30mg seems a bit high based on everything I've reae, I will be sticking with 15mg for 3 months, I'd prefer not to get riddled with bloat and blood pressure.

Ya no bud, 30mg makes me feel like crap. sticking to 15mg for this round

Any indication of hepatotoxicity?